Ocular Delivery

Ophthalmic Silica Eye Drops

Sustained Release with Topical Administration

DelSiTech’s Silica Eye Drop formulation is designed to provide up to 24-hour controlled release of the drug in the tear fluid with once-daily application.

Key benefits include:

• once-a-day dosing
• support for sustained drug levels for up to 24 hours
• stabilisation of the drug
• supports steady-state dosing with minimal fluctuation
• has shown potential to maintain therapeutic drug levels even overnight
• comfortable application and well tolerated in Phase 1 clinical studies

These eye drops offer a promising approach to non-invasive ocular therapy, addressing common limitations of conventional topical drops such as poor bioavailability, rapid drainage, and low patient compliance.

Injectable Silica for Intravitreal Delivery

Sustained Release with Intravitreal Administration

DelSiTech’s Injectable Silica formulation is designed to provide long-acting drug release in the back of the eye, with durations ranging from a few weeks to six months or more.

Key benefits include:

• sustained drug release lasting several months
• near zero-order release, supporting consistent release rates
• low burst or burst-free release supporting controlled delivery
• reduced administration frequency
• minimal invasiveness, with administration via a 30-gauge needle