Controlled release of biological macromolecules

With DelSiTech's silica matrix you can administer peptides, proteins, RNA, DNA and complex carbohydrates in a controlled fashion.

DelSiTechTMSilica Matrix is the method of choice for controlled drug delivery of biological macromolecules. We have succesfully developed formulations for protein drug delivery and some of our work with model proteins have been published (read more here). The protein release rate is strictly controlled by silica biodegradation and the biological activity of encapsulated proteins is well preserved. Also complex carbohydrates such as heparins can be administered with our technology. In addition, DelSiTechTMSilica Matrix is well suited for drug delivery of therapeutic RNA molecules (e.g. siRNA) and DNA plasmids where conventional administration methods often fail.